Abstract
Glycine Betaine is a quaternary amino compound that accumulates in stress conditions, mainly abiotic stresses like drought and salinity & synthesized by the two-step oxidation of choline via the intermediate betaine aldehyde, catalyzed by Choline monooxygenase and Betaine aldehyde dehydrogenase (BADH).The sequence analysis of key enzymes of Glycine betaine biosynthesis i.e. BADH was carried out using various online proteomic tools available on Expasy and EBL, and then homologous modeling of this enzyme was performed using automated mode SWISS-MODEL & GENO 3D and models were analyzed on QMEAN. This was an attempt to find the possible model of BADH, because no physical model of BADH is yet available on PDB.
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Kumar Bhati, K., Kumar Singh, V. Betaine aldehyde dehydrogenase (BADH) from Hordeum vulgare- an in-silico study. Nat Prec (2011). https://doi.org/10.1038/npre.2011.6360.1
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DOI: https://doi.org/10.1038/npre.2011.6360.1