Rsp5 promotes Gene Activation mediated by 9aaTAD Transcription Factors Oaf1 and Gal4

Abstract

Nine-amino-acid transactivation domain, 9aaTAD, defines a large superfamily of yeast and mammals transcription factors. The transactivation of the 9aaTAD has been addressed to multiple general co-activators TAF9, MED15, CBP and p300. We demonstrate for the 9aaTAD transcription factors Oaf1 and Gal4 functional and physical interaction with E3-Ubiquitin Ligase Rsp5. The Rsp5-associations with RNA polymerase II and TFIID were reported previously.

Author information

Affiliations

Authors

Corresponding author

Correspondence to Martin Piskacek.

Rights and permissions

Creative Commons Attribution 3.0 License.

Reprints and Permissions

About this article

Cite this article

Lipp, J., Koranda, M. & Piskacek, M. Rsp5 promotes Gene Activation mediated by 9aaTAD Transcription Factors Oaf1 and Gal4 . Nat Prec (2009). https://doi.org/10.1038/npre.2009.3968.1

Download citation

Keywords

  • transcription TFIID SAGA

Search

Quick links

Sign up for the Nature Briefing newsletter for a daily update on COVID-19 science.
Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing