Abstract
The Ontology-Based eXtensible data model (OBX) was developed to serve as a framework for the development of a clinical research database in the Immunology Database and Analysis Portal (ImmPort) system. OBX was designed around the logical structure provided by the Basic Formal Ontology (BFO) and the Ontology for Biomedical Investigations (OBI). By using the logical structure provided by these two well-formulated ontologies, we have found that a relatively simple, extensible data model could be developed to represent the relatively complex domain of clinical research. In addition, the common framework provided by the BFO should make it straightforward to utilize OBX database data dictionaries based on reference and application ontologies from the OBO Foundry.
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Scheuermann, R., Kong, M., Dahlke, C. et al. An Ontology-Based Framework for Clinical Research Databases. Nat Prec (2009). https://doi.org/10.1038/npre.2009.3482.1
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DOI: https://doi.org/10.1038/npre.2009.3482.1