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Mobile small RNAs: Sperm–companion communication

A series of genetic experiments demonstrates that small RNAs can direct gene silencing within germ cells in a non-cell-autonomous manner. This provides evidence for how plant germ and non-germ cells may communicate to maintain genome integrity during reproductive transitions.

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Figure 1: A model of how siRNAs derived from companion cells may mediate silencing in germ cells.


  1. Martínez, G., Panda, K., Köhler, C. & Slotkin, R. K. Nature Plants 2, 16030 (2016).

    Article  Google Scholar 

  2. Slotkin, R. K. et al. Cell 136, 461–472 (2009).

    CAS  Article  Google Scholar 

  3. Schoft, V. K. et al. EMBO Rep. 10, 1015–1021 (2009).

    CAS  Article  Google Scholar 

  4. Grant-Downton, R. et al. Curr. Biol. 23, R599–R601 (2013).

    CAS  Article  Google Scholar 

  5. Marí-Ordóñez, A. et al. Nature Genet. 45, 1029–1039 (2013).

    Article  Google Scholar 

  6. Felippes, F. F. D., Ott, F. & Weigel, D. Nucleic Acids Res. 39, 2880–2889 (2011).

    Article  Google Scholar 

  7. McCue, A. D., Nuthikattu, S., Reeder, S. H. & Slotkin, R. K. PLoS Genet. 8, e1002474 (2012).

    CAS  Article  Google Scholar 

  8. Aravin, A. A., Hannon, G. J. & Brennecke, J. Science 318, 761–764 (2007).

    CAS  Article  Google Scholar 

  9. Chalker, D. L., Meyer, E. & Mochizuki, K. Cold Spring Harb. Persp. Biol. 5, a017764–a017764 (2013).

    Article  Google Scholar 

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Correspondence to Michael D. Nodine.

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Nodine, M. Mobile small RNAs: Sperm–companion communication. Nature Plants 2, 16041 (2016).

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