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Immunity: Flagellin seen from all sides

Many plants detect bacteria by the receptor FLS2 that binds the flagellin epitope flg22. A new pattern recognition receptor FLS3 in tomato detects flagellin from a second side; a further move in the evolutionary game of ‘hide and seek’ where pathogens evade recognition and hosts evolve novel immunoreceptors to detect them.

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Figure 1: Distinct epitopes of flagellin are recognized by different PRRs from plants and animals.

References

  1. Boller, T. & Felix, G. Annu. Rev. Plant Biol. 60, 379–406 (2009).

    Article  CAS  Google Scholar 

  2. Hind, S. R. et al. Nat. Plants 2, 16128 (2016).

    Article  CAS  Google Scholar 

  3. Cai, R. et al. PLoS Pathog. 7, e1002130 (2011).

    Article  CAS  Google Scholar 

  4. Clarke, C. R. et al. New Phytol. 200, 847–860 (2013).

    Article  CAS  Google Scholar 

  5. Rossez, Y., Wolfson, E. B., Holmes, A., Gally, D. L. & Holden, N. J. PLoS Pathog. 11, e1004483 (2015).

    Google Scholar 

  6. Gómez-Gómez, L. & Boller, T. Mol. Cell 5, 1003–1011 (2000).

    Article  Google Scholar 

  7. Hayashi, F. et al. Nature 410, 1099–1103 (2001).

    Article  CAS  Google Scholar 

  8. Zhao, Y. et al. Nature 477, 596–600 (2011).

    Article  CAS  Google Scholar 

  9. Felix, G., Duran, J. D., Volko, S. & Boller, T. Plant J. 18, 265–276 (1999).

    Article  CAS  Google Scholar 

  10. Katsuragi, Y. et al. Mol. Plant Microbe In. 28, 648–58 (2015).

    Article  CAS  Google Scholar 

  11. Hirai, H. et al. J. Biol. Chem. 286, 25519–25530 (2011).

    Article  CAS  Google Scholar 

  12. Albert, M. et al. Eur. J. Cell Biol. 89, 200–207 (2010).

    Article  CAS  Google Scholar 

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Correspondence to Georg Felix.

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Fliegmann, J., Felix, G. Immunity: Flagellin seen from all sides. Nature Plants 2, 16136 (2016). https://doi.org/10.1038/nplants.2016.136

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