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Protein physics

Forever ageing

Single-molecule techniques have long given us insight into the motion and interactions of individual molecules. But simulations now show that the dynamics inside single proteins is not as simple as we thought — and that proteins are forever changing.

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Figure 1: The simulations of Hu et al.6 measure the relative distance d(t) of two amino acids that are remote to each other in terms of the chemical co-ordinate along the protein backbone.

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Correspondence to Ralf Metzler.

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Metzler, R. Forever ageing. Nature Phys 12, 113–114 (2016). https://doi.org/10.1038/nphys3585

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