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Biophotonics

Through-skull brain imaging

The use of carbon nanotubes makes it possible to perform fluorescent imaging of cerebral vasculature of mice through their intact skulls. The high spatial and temporal resolution of the non-invasive technique may prove useful for studies of stroke and other brain disorders.

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Figure 1: Schematic of the single-walled carbon nanotube (SWNT) fluorescence approach for imaging mouse cerebral vasculature through intact skull and scalp.
Figure 2: Image of mouse cerebral vasculature generated by single-walled carbon nanotube fluorescence with high contrast and resolution.

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References

  1. Strong, A. J. et al. J. Cereb. Blood Flow Metab. 26, 645–653 (2006).

    Article  Google Scholar 

  2. Luo, Z. C., Yuan, Z. J., Pan, Y. T. & Du, C. W. Opt. Lett. 34, 1480–1482 (2009).

    Article  ADS  Google Scholar 

  3. Hong, G. et al. Nature Photon. 8, 723–730 10.1038/nphoton.2014.166(2014).

    Article  ADS  Google Scholar 

  4. Cheong, W.-F., Prahl, S. A. & Welch, A. J. IEEE J. Quantum Electron. 26, 2166–2185 (1990).

    Article  ADS  Google Scholar 

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Correspondence to Steen J. Madsen.

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Madsen, S. Through-skull brain imaging. Nature Photon 8, 677–678 (2014). https://doi.org/10.1038/nphoton.2014.205

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