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Host response: Pregnancy impairs flu defences

It is unclear why pregnant women are at high risk of severe influenza infection. Allogeneic pregnancy in mice is now shown to alter both innate and adaptive responses to influenza virus infection, enabling the emergence of more virulent virus variants.

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Figure 1: Increasingly varied influenza virus during pregnancy.


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Correspondence to Elodie Ghedin.

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The authors declare no competing financial interests.

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Ghedin, E., Schultz-Cherry, S. Host response: Pregnancy impairs flu defences. Nat Microbiol 2, 17077 (2017).

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