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Bacterial pathogenesis: Remodelling recurrent infection

Bacterial infection of the bladder can lead to mucosal remodelling and increased predisposition to recurrent infection, changing the way we view host susceptibility and providing new opportunities to develop novel therapeutics.

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Figure 1: Features of UPEC colonization and host response in rUTI.

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Correspondence to Glen C. Ulett or Mark A. Schembri.

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Ulett, G., Schembri, M. Bacterial pathogenesis: Remodelling recurrent infection. Nat Microbiol 2, 16256 (2017). https://doi.org/10.1038/nmicrobiol.2016.256

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