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Single protein complex visualization: Seeing is believing

Protein-protein interactions are at the heart of the cellular machinery. Direct in-cell visualization of single, endogenous protein interaction pairs now becomes possible.

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Figure 1: FRET, BiFC and P-LISA each allow the in-cell visualization of protein complexes through monitoring fluorescence.

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Lievens, S., Tavernier, J. Single protein complex visualization: Seeing is believing. Nat Methods 3, 971–972 (2006). https://doi.org/10.1038/nmeth1206-971

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