Methods relying on dense arrays of synthetic oligodeoxynucleotides to target specific subsets of the human genome may enable routine resequencing of all human exons or multi-megabase-pair chromosomal regions.
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References
- 1
Porreca, J.G. et al. Nat. Methods 4, 931–936 (2007).
- 2
Okou, T.D. et al. Nat. Methods 4, 907–909 (2007).
- 3
Albert, T.J. et al. Nat. Methods 4, 903–905 (2007).
- 4
Shendure, J. et al. Nat. Rev. Genet. 5, 335–344 (2004).
- 5
Nilsson, M. et al. Science 265, 2085–2088 (1994).
- 6
Hardenbol, P. et al. Nat. Biotechnol. 21, 673–678 (2003).
- 7
Bashiardes, S. et al. Nat. Methods 2, 63–69 (2005).
- 8
Guo, Z. et al. Proc. Natl. Acad. Sci. USA 103, 6964–6969 (2006).
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Olson, M. Enrichment of super-sized resequencing targets from the human genome. Nat Methods 4, 891–892 (2007). https://doi.org/10.1038/nmeth1107-891
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