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Enrichment of super-sized resequencing targets from the human genome

Methods relying on dense arrays of synthetic oligodeoxynucleotides to target specific subsets of the human genome may enable routine resequencing of all human exons or multi-megabase-pair chromosomal regions.

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Figure 1: Two ways to use high-density arrays of custom-synthesized oligodeoxynucleotides to target subsets of the human genome.

Kim Caesar

References

  1. 1

    Porreca, J.G. et al. Nat. Methods 4, 931–936 (2007).

    CAS  Article  Google Scholar 

  2. 2

    Okou, T.D. et al. Nat. Methods 4, 907–909 (2007).

    CAS  Article  Google Scholar 

  3. 3

    Albert, T.J. et al. Nat. Methods 4, 903–905 (2007).

    CAS  Article  Google Scholar 

  4. 4

    Shendure, J. et al. Nat. Rev. Genet. 5, 335–344 (2004).

    CAS  Article  Google Scholar 

  5. 5

    Nilsson, M. et al. Science 265, 2085–2088 (1994).

    CAS  Article  Google Scholar 

  6. 6

    Hardenbol, P. et al. Nat. Biotechnol. 21, 673–678 (2003).

    CAS  Article  Google Scholar 

  7. 7

    Bashiardes, S. et al. Nat. Methods 2, 63–69 (2005).

    CAS  Article  Google Scholar 

  8. 8

    Guo, Z. et al. Proc. Natl. Acad. Sci. USA 103, 6964–6969 (2006).

    CAS  Article  Google Scholar 

Download references

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Olson, M. Enrichment of super-sized resequencing targets from the human genome. Nat Methods 4, 891–892 (2007). https://doi.org/10.1038/nmeth1107-891

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