Two groups used quantitative mass spectrometry to look at changes in protein phosphorylation across the cell cycle.
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References
Dephoure, N. et al. A quantitative atlas of mitotic phosphorylation. Proc. Natl. Acad. Sci. USA 105, 10762–10767 (2008).
Daub, H. et al. Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. Mol. Cell 31, 438–448 (2008).
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Doerr, A. Phosphorylation and the cell cycle. Nat Methods 5, 858–859 (2008). https://doi.org/10.1038/nmeth1008-858b
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DOI: https://doi.org/10.1038/nmeth1008-858b
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