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Soaking up small RNAs

Nature Methods volume 4, pages 694–695 (2007)Cite this article

MicroRNAs are not amenable to classical RNAi-based knockdown strategies, but genetic 'sponges' that compete microRNAs away from their natural targets create a microRNA 'knockdown'.

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Figure 1: miRNA sponges interfere with miRNA function.

Katie Ris-Vicari

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  1. Department of Cell and Developmental Biology, University of North Carolina, Chapel Hill, 27599, North Carolina, USA

    Scott M Hammond

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  1. Scott M Hammond
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Hammond, S. Soaking up small RNAs. Nat Methods 4, 694–695 (2007). https://doi.org/10.1038/nmeth0907-694

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