Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Experimental challenge to a 'rigorous' BRET analysis of GPCR oligomerization

Your institute does not have access to this article

Relevant articles

Open Access articles citing this article.

Access options

Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.

Figure 1: 'Type 2 experiments' for β2AR, D1 and D2-dopamine receptors.


  1. James, J.R., Oliveira, M.I., Carmo, A.M., Iaboni, A. & Davis, S.J. Nat. Methods 3, 1001–1006 (2006).

    CAS  Article  Google Scholar 

  2. Bouvier, M., Heveker, N., Jockers, R., Marullo, S. & Milligan, G. Nat. Methods 4, 3–4 (2007).

    CAS  Article  Google Scholar 

  3. Mercier, J.F., Salahpour, A., Angers, S., Breit, A. & Bouvier, M. J. Biol. Chem. 277, 44925–44931 (2002).

    CAS  Article  Google Scholar 

  4. Breit, A., Lagacé, M. & Bouvier, M. J. Biol. Chem. 279, 28756–28765 (2004).

  5. Wang, D., Sun, X., Bohn, L.M. & Sadee, W. Mol. Pharmacol. 67, 2173–2184 (2005).

    CAS  Article  Google Scholar 

  6. Hamdan, F.F., Audet, M., Garneau, P., Pelletier, J. & Bouvier M. J. Biomol. Screen. 5, 463–475 (2005).

    Article  Google Scholar 

Download references


We thank M. Caron for support and critical reading of the manuscript, and A. Ramsey for critical reading of the manuscript. Supported by a fellowship from Canadian Institutes of Health Research (A.S.) and by a fellowship from Fondation pour la Recherche Médicale, France (B.M.).

Author information

Authors and Affiliations


Ethics declarations

Competing interests

The authors declare no competing financial interests.

Supplementary information

Supplementary Text and Figures

Supplementary Figure 1, Supplementary Tables 1–2, Supplementary Methods (PDF 224 kb)

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Salahpour, A., Masri, B. Experimental challenge to a 'rigorous' BRET analysis of GPCR oligomerization. Nat Methods 4, 599–600 (2007).

Download citation

  • Issue Date:

  • DOI:

Further reading


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing