Streptavidin surprises

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Reengineered streptavidin mutants bind biotin-4-fluorescein with extremely tight yet reversible binding affinity.

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    Aslan, F.M. et al. Engineered single-chain dimeric streptavidins with an unexpected strong preference for biotin-4-fluorescein. Proc. Natl. Acad. Sci. USA 102, 8507–8512 (2005).

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Doerr, A. Streptavidin surprises. Nat Methods 2, 573 (2005) doi:10.1038/nmeth0805-573

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