A carefully thought out method of harvesting and arraying tissue samples into blocks provides a simple but powerful way of reliably producing extremely large tissue microarrays using commonly available laboratory equipment.
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References
LeBaron, M.J. et al. Ultrahigh density microarrays of solid samples. Nat. Methods 2, 511–513 (2005).
Battifora, H. The multitumor (sausage) tissue block: novel method for immunohistochemical antibody testing. Lab Invest. 55, 244–248 (1986).
Wan, W.H., Fortuna, M.B. & Furmanski, P. A rapid and efficient method for testing immunohistochemical reactivity of monoclonal antibodies against multiple tissue samples simultaneously. J. Immunol. Methods 103, 121–129 (1987).
Kononen, J. et al. Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nat. Med. 4, 844–847 (1998).
Camp, R.L., Chung, G.G. & Rimm, D.L. Automated subcellular localization and quantification of protein expression in tissue microarrays. Nat. Med. 8, 1323–1327 (2002).
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Rimm, D. Tissue microarrays without cores. Nat Methods 2, 492–493 (2005). https://doi.org/10.1038/nmeth0705-492
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DOI: https://doi.org/10.1038/nmeth0705-492
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REporting recommendations for tumour MARKer prognostic studies (REMARK)
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