Keeping it in the family

Article metrics

Whole-genome sequencing of DNA from two children with Mendelian disorders and from their healthy parents allows efficient correction of sequencing errors and the identification of causal genes.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Roach, J.C. et al. Analysis of genetic inheritance in a family quartet by whole-genome sequencing. Science advance online publication (11 March 2010).

Download references

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Rusk, N. Keeping it in the family. Nat Methods 7, 350 (2010) doi:10.1038/nmeth0510-350

Download citation