Intensity normalization improves color calling in SOLiD sequencing

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Figure 1: Effect of normalization on color proportions and SNP calling.

References

  1. 1

    McKernan, K.J., et al. Genome Res. 19, 1527–1541 (2009).

  2. 2

    Tang, F. et al. Nat. Methods 6, 377–382 (2009).

  3. 3

    Bravo, H.C. & Irizarry, R.A. Biometrics advance online publication, 13 November 2009 (doi: 10.1111/j.1541-0420.2009.01353.x).

  4. 4

    Quinlan, A.R., Stewart, D.A., Stromberg, M.P. & Marth, G. Nat. Methods 5, 179–181 (2008).

  5. 5

    Kao, W.C., Stevens, K. & Song, Y.S. Genome Res. 19, 1884–1895 (2009).

  6. 6

    Hayden, E.C. Nature 451, 378–379 (2008).

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Correspondence to Hao Wu or Héctor Corrada Bravo.

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The authors declare no competing financial interests.

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Supplementary Figure 1, Supplementary Tables 1–4, Supplementary Methods (PDF 1021 kb)

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Wu, H., Irizarry, R. & Bravo, H. Intensity normalization improves color calling in SOLiD sequencing. Nat Methods 7, 336–337 (2010) doi:10.1038/nmeth0510-336

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