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Designer receptors for every body

Nature Methods volume 4, pages 382–383 (2007)Cite this article

Abstract

Using a directed evolution approach, researchers demonstrate a way of creating 'designer' receptors that are specifically activated by a ligand with no other biological activity in the cell.

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References

  1. Armbruster, B.N. et al. Evolving the lock to fit the key to create a family of G protein–coupled receptors potently activated by an inert ligand. Proc. Natl. Acad. Sci. USA 104, 5163–5168 (2007).

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Authors
  1. Irene Kaganman
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Kaganman, I. Designer receptors for every body. Nat Methods 4, 382–383 (2007). https://doi.org/10.1038/nmeth0507-382b

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  • DOI: https://doi.org/10.1038/nmeth0507-382b

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