Abstract
Artificial scaffolds composed of carefully chosen protein domains permit protein complexes to be assembled in vitro, providing a line of sight to construct multiprotein architectures that mimic native complexes in vivo.
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References
Diehl, M.R. et al. Engineering cooperativity in biomotor-protein assemblies. Science 311, 1468–1471 (2006).
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Evanko, D. Mimicking nature with protein scaffolds. Nat Methods 3, 334–335 (2006). https://doi.org/10.1038/nmeth0506-334b
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DOI: https://doi.org/10.1038/nmeth0506-334b