A team of researchers applied a 'discovery single-particle profiling' experimental strategy to visualize the assembly of the ribosome via time-resolved electron microscopy.
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References
Mulder, A.M. et al. Visualizing ribosome biogenesis: parallel assembly pathways for the 30S subunit. Science 330, 673–677 (2010).
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Doerr, A. The birth of a ribosome. Nat Methods 8, 12–13 (2011). https://doi.org/10.1038/nmeth0111-12a
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DOI: https://doi.org/10.1038/nmeth0111-12a