The authors are funded to produce mouse models using Cas9 as part of the International Mouse Phenotyping Consortium from Genome Canada and Ontario Genomics OGI-051 (L.M.J.N.), the National Human Genome Research Institute, the NIH Common Fund, through the Office of Strategic Coordination/Office of the NIH Director, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Cancer Institute, National Institute of Neurological Disorders and Stroke, National Institute on Deafness and Other Communication Disorders, National Institute of Environmental Health Sciences, National Institute of Drug Abuse and the Office of Research on Women's Health awards UM1HG006348 (J.D.H., J.R.S., L.T., S.D.M.B.), UM1OD023321 (L.M.J.N., K.C.L.) and UM1OD023222 (S.D.M.) and MRC IMPC Strategic Award 53658 (L.T., S.D.M.B.).