Research Highlights | Published:

Biochemistry

CRISPR kinetics

Nature Methods volume 14, pages 650651 (2017) | Download Citation

In vitro Cas9-binding assays show the effects of mutations in the target sequence on binding kinetics.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    et al. High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding. Proc. Nat. Acad. Sci. U.S.A. 114, 5461–5466 (2017).

Download references

About this article

Publication history

Published

DOI

https://doi.org/10.1038/nmeth.4360

Authors

  1. Search for Nicole Rusk in:

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing