Correspondence | Published:

Impact of outdated gene annotations on pathway enrichment analysis

Nature Methods volume 13, pages 705706 (2016) | Download Citation

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    et al. Nat. Methods 12, 615–621 (2015).

  2. 2.

    et al. Nat. Genet. 25, 25–29 (2000).

  3. 3.

    et al. Nucleic Acids Res. 42, D472–D477 (2014).

  4. 4.

    , , , & Nucleic Acids Res. 35, W193–W200 (2007).

  5. 5.

    , & Nucleic Acids Res. 41, D377–D386 (2013).

  6. 6.

    , & Nat. Protoc. 4, 44–57 (2009).

  7. 7.

    et al. Cell 164, 293–309 (2016).

  8. 8.

    et al. Sci. Rep. 3, 2650 (2013).

  9. 9.

    et al. Nat. Neurosci. 16, 1373–1382 (2013).

  10. 10.

    et al. Nat. Rev. Clin. Oncol. 12, 445–464 (2015).

Download references

Acknowledgements

We thank the reviewers and the bioRxiv community for insightful comments. This study was supported by the Ontario Institute for Cancer Research (Investigator Award to J.R.).

Author information

Affiliations

  1. Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.

    • Lina Wadi
    • , Mona Meyer
    • , Joel Weiser
    • , Lincoln D Stein
    •  & Jüri Reimand
  2. Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.

    • Lincoln D Stein
  3. Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.

    • Jüri Reimand

Authors

  1. Search for Lina Wadi in:

  2. Search for Mona Meyer in:

  3. Search for Joel Weiser in:

  4. Search for Lincoln D Stein in:

  5. Search for Jüri Reimand in:

Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Jüri Reimand.

Integrated supplementary information

Supplementary information

PDF files

  1. 1.

    Supplementary Text and Figures

    Supplementary Figures 1–14, Supplementary Tables 1–5, Supplementary Note and Supplementary Methods

About this article

Publication history

Published

DOI

https://doi.org/10.1038/nmeth.3963

Further reading

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing