Sensors and probes

Making sense of NAD+ subcellular localization

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A fluorescent NAD+ biosensor targeted to specific cellular compartments detects local fluctuation in NAD+ concentration.

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References

  1. 1

    Cambronne, X.A. et al. Biosensor reveals multiple sources for mitochondrial NAD+. Science 352, 1474–1477 (2016).

  2. 2

    Cameron, W.D. et al. Apollo-NADP+: a spectrally tunable family of genetically encoded sensors for NADP+. Nat. Methods 13, 352–358 (2016).

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