Anion channelrhodopsins, recently discovered in cryptophyte algae, can be used as highly efficient optogenetic tools to inhibit neurons.
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References
Govorunova, E.G. et al. Natural light-gated anion channels: a family of microbial rhodopsins for advanced optogenetics. Science 349, 647–650 (2015).
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Vogt, N. Algae are the best engineers of optogenetic inhibitors. Nat Methods 12, 806–807 (2015). https://doi.org/10.1038/nmeth.3571
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DOI: https://doi.org/10.1038/nmeth.3571