Genomics

Bacterial genomes by the droplet

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To produce enough raw material for high-quality whole-genome sequencing, researchers capture and grow single, culture-resistant bacteria in gel micro-droplets.

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References

  1. 1

    Fitzsimons, M.S. et al. Nearly finished genomes produced using gel microdroplet culturing reveal substantial intraspecies genomic diversity within the human microbiome. Genome Res. doi:10.1101/gr.142208.112 (14 March 2013).

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Nawy, T. Bacterial genomes by the droplet. Nat Methods 10, 386 (2013) doi:10.1038/nmeth.2469

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