Scaling up the systematic hunt for mammalian genetic interactions

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Three RNA interference–based methods probe genetic interactions in mammalian cells at large scale.

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Figure 1: Three different approaches to genetic interaction screens in mammalian cells based on arrayed and pooled RNAi technologies.

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Correspondence to Jason Moffat.

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The authors declare no competing financial interests.

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Hart, T., Moffat, J. Scaling up the systematic hunt for mammalian genetic interactions. Nat Methods 10, 397–399 (2013) doi:10.1038/nmeth.2449

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