Researchers adapt a popular Orbitrap-based mass spectrometer to detect and analyze large, intact protein complexes, accelerating a new frontier in structural biology.
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N.L.K. holds a sponsored research agreement with Thermo Scientific, the company that produces the Exactive Plus. P.D.C. executes the agreement.
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Compton, P., Kelleher, N. Spinning up mass spectrometry for whole protein complexes. Nat Methods 9, 1065–1066 (2012). https://doi.org/10.1038/nmeth.2216
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DOI: https://doi.org/10.1038/nmeth.2216
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