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Hitting the sweet spot

Nature Methods volume 9, pages 451–453 (2012)Cite this article

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A strategy that uses genetically encoded GFP-tagged antibodies allows in vivo imaging of extracellular non–genetically encoded molecules.

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Figure 1: Visualizing epitopes in vivo.

References

  1. Attreed, M., Desbois, M., van Kuppevelt, T.H. & Bülow, H.E. Nat. Methods 9, 477–479 (2012).

    Article  CAS  Google Scholar 

  2. Bülow, H.E. & Hobert, O. Annu. Rev. Cell Dev. Biol. 22, 375–407 (2006).

    Article  Google Scholar 

  3. van Kuppevelt, T.H., Dennissen, M.A., van Venrooij, W.J., Hoet, R.M. & Veerkamp, J.H. J. Biol. Chem. 273, 12960–12966 (1998).

    Article  CAS  Google Scholar 

  4. Ten Dam, G.B. et al. J. Biol. Chem. 281, 4654–4662 (2006).

    Article  CAS  Google Scholar 

  5. Townley, R.A. & Bülow, H.E. J. Biol. Chem. 286, 16824–16831 (2011).

    Article  CAS  Google Scholar 

  6. Feinberg, E.H. et al. Neuron 57, 353–363 (2008).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Gauri Kulkarni and William G. Wadsworth are in the Department of Pathology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, New Jersey, USA.,

    Gauri Kulkarni & William G Wadsworth

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  1. Gauri Kulkarni
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  2. William G Wadsworth
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Correspondence to William G Wadsworth.

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The authors declare no competing financial interests.

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Kulkarni, G., Wadsworth, W. Hitting the sweet spot. Nat Methods 9, 451–453 (2012). https://doi.org/10.1038/nmeth.1987

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