Chromatin immunoprecipitation and yeast one-hybrid systems are complementary approaches to identify protein-DNA interactions. Improvements to these methods now make them more versatile and high-throughput, and should lead to the generation of rich datasets for the study of gene regulation.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Mazzoni, E.O. et al. Nat. Methods 8, 1056–1058 (2011).
Gaudinier, A. et al. Nat. Methods 8, 1053–1055 (2011).
Reece-Hoyes, J.S. et al. Nat. Methods 8, 1050–1052 (2011).
Hens, K. et al. Nat. Methods 8, 1065–1070 (2011).
Reece-Hoyes, J.S. et al. Nat. Methods 8, 1059–1064 (2011).
Johnson, D.S. et al. Science 316, 1497–1502 (2007).
Deplancke, B. et al. Genome Res. 14, 2093–2101 (2004).
Ni, J.Q. et al. Nat. Methods 8, 405–407 (2011).
Yuh, C.H. et al. Science 279, 1896–1902 (1998).
Clyde, D.E. et al. Nature 426, 849–853 (2003).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Ozdemir, A., Stathopoulos, A. Exciting times: bountiful data to facilitate studies of cis-regulatory control. Nat Methods 8, 1016–1017 (2011). https://doi.org/10.1038/nmeth.1795
Published:
Issue Date:
DOI: https://doi.org/10.1038/nmeth.1795
