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Channeling the data deluge

Nature Methods volume 8, pages 463465 (2011) | Download Citation

With vast increases in biological data generation, mechanisms for data storage and analysis have become limiting. A data structure, semantically typed data hypercubes (SDCubes), that combines hierarchical data format version 5 (HDF5) and extensible markup language (XML) file formats, now permits the flexible storage, annotation and retrieval of large and heterogenous datasets.

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Author information


  1. JJason R. Swedlow is at the Wellcome Trust Centre for Gene Regulation and Expression, College of Life Sciences, University of Dundee, Dundee, Scotland, UK.

    • Jason R Swedlow
    • , Gianluigi Zanetti
    •  & Christoph Best
  2. Gianluigi Zanetti is at the Center for Advanced Studies, Research and Development in Sardinia, Pula, Italy.

  3. Christoph Best is at Google UK Ltd., London, UK.


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Competing interests

J.R.S. founded and directs the Open Microscopy Environment and Glencoe Software, Inc., which build data management solutions for imaging in the life sciences. C.B. is employed by Google UK, Ltd., which delivers search and data tools for the world community.

Corresponding author

Correspondence to Jason R Swedlow.

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