Control of piezoelectricity in amino acids by supramolecular packing

Abstract

Piezoelectricity, the linear relationship between stress and induced electrical charge, has attracted recent interest due to its manifestation in biological molecules such as synthetic polypeptides or amino acid crystals, including gamma (γ) glycine. It has also been demonstrated in bone, collagen, elastin and the synthetic bone mineral hydroxyapatite. Piezoelectric coefficients exhibited by these biological materials are generally low, typically in the range of 0.1–10 pm V−1, limiting technological applications. Guided by quantum mechanical calculations we have measured a high shear piezoelectricity (178 pm V−1) in the amino acid crystal beta (β) glycine, which is of similar magnitude to barium titanate or lead zirconate titanate. Our calculations show that the high piezoelectric coefficients originate from an efficient packing of the molecules along certain crystallographic planes and directions. The highest predicted piezoelectric voltage constant for β-glycine crystals is 8 V mN−1, which is an order of magnitude larger than the voltage generated by any currently used ceramic or polymer.

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Figure 1: Supramolecular packing directs piezoelectric response in glycine amino acid crystals.
Figure 2: From simulation to experimental verification.
Figure 3: Controlling polymorphic transitions in glycine crystals.
Figure 4: Simple energy harvesting method using γ-glycine crystals.

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Acknowledgements

The authors thank E. O’Connell, A. Stewart and U. Bangert for use of their optical microscope. This publication has emanated from research conducted with the financial support of Science Foundation Ireland (SFI) and is co-funded under the European Regional Development Fund under Grant Number 13/RC/2073. D.T. acknowledges support from SFI under Grant Number 15/CDA/3491, and for provision of computing resources at the SFI/Higher Education Authority Irish Center for High-End Computing (ICHEC). A.L.K. acknowledges support from CICECO—Aveiro Institute of Materials (Ref. FCT UID/CTM/50011/2013), financed by national funds through the FCT/MEC and when applicable co-financed by FEDER under the PT2020 Partnership Agreement. Funding from the Irish Research Council EMBARK Postgraduate Scholarship (RS/2012/337) to A.S. is acknowledged. S.A.M.T. acknowledges Enterprise Ireland and Erasmus for their long-standing support and funding.

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Contributions

S.G. performed the computer simulations. S.G. and A.S. performed piezoelectric experiments. S.G. and D.C. determined crystallographic orientations and the magnitude of polarization in glycine polymorphs. S.G. grew glycine crystals in collaboration with M.R.N., T.S. and A.L.K. R.M. performed Raman characterization and mapping. M.G. performed XRD analysis under supervision of N.L. and C.S. C.M. performed SEM characterization under supervision of F.M.F.R. S.A.M.T. and D.T. designed and supervised the project. All authors contributed to writing the manuscript.

Corresponding authors

Correspondence to Syed A. M. Tofail or Damien Thompson.

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Guerin, S., Stapleton, A., Chovan, D. et al. Control of piezoelectricity in amino acids by supramolecular packing. Nat. Mater. 17, 180–186 (2018). https://doi.org/10.1038/nmat5045

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