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Protein polymers

Encoding phase transitions

Intrinsically disordered protein polymers can be designed to encode tunable lower or upper critical solution temperatures in physiological solutions.

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Figure 1: A two-component mixture can exist as a well-mixed, one-phase system, or as a two-phase system where the two components segregate into polymer-rich and solvent-rich phases.

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Correspondence to Rohit V. Pappu.

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Holehouse, A., Pappu, R. Encoding phase transitions. Nature Mater 14, 1083–1084 (2015). https://doi.org/10.1038/nmat4459

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