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Cellular mechanotransduction

Stiffness does matter

Extracellular-matrix stiffness regulates cell behaviour even when decoupled from ligand density and tethering.

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Figure 1: Matrix stiffness and ligand density, rather than adhesive-ligand tethering, regulate cell behaviour.

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Correspondence to Sanjay Kumar.

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Kumar, S. Stiffness does matter. Nature Mater 13, 918–920 (2014). https://doi.org/10.1038/nmat4094

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