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Absence of ST7 mutations in tumor-derived cell lines and tumors

Nature Genetics volume 29, pages 380–381 (2001)Cite this article

Abstract

The gene ST7 has been proposed as the multi-tissue tumor-suppressor gene (TSG) at chromosome 7q31.1. However, we have sought and failed to detect the truncating mutations reported to exist in this gene.

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Figure 1: ST7 wildtype sequence in tumor-derived cell lines.

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References

  1. Zenklusen, J.C. & Conti, C.J. Mol. Carcinog. 15, 167–175 (1996).

    Article  CAS  Google Scholar 

  2. Ogata, T. et al. Mol. Cell. Biol. 13, 6036–6043 (1993).

    Article  CAS  Google Scholar 

  3. Black, D.M. Br. J. Cancer 80, 42–45 (1999).

    CAS  PubMed  Google Scholar 

  4. Hurlstone, A.F.L. et al. Oncogene 18, 1881–1890 (1999).

    Article  CAS  Google Scholar 

  5. Tobias, E.S., Hurlstone, A.F.L., MacKenzie, E., McFarlane, R. & Black, D.M. Oncogene 20, 2844–2853 (2001).

    Article  CAS  Google Scholar 

  6. Vincent, J.B. et al. Am. J. Hum. Genet. 67, 510–514 (2000).

    Article  CAS  Google Scholar 

  7. Zenklusen, J.C., Conti, C.J. & Green, E.D. Nature Genet. 27, 392–398 (2001).

    Article  CAS  Google Scholar 

  8. Rommens, J.M. et al. Science 245, 1059–1065 (1989).

    Article  CAS  Google Scholar 

  9. Hurlstone, A.F.L. Thesis, Univ. Glasgow (1998).

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Acknowledgements

This work was supported by a program grant from The Cancer Research Campaign.

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Authors and Affiliations

  1. The Cancer Research Campaign Laboratories, Beatson Institute for Cancer Research, Switchback Road, Bearsden, G61 1BD, Glasgow, UK

    Kate A. Hughes, Adam F.L. Hurlstone, Edward S. Tobias, Robert McFarlane & Donald M. Black

Authors
  1. Kate A. Hughes
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  2. Adam F.L. Hurlstone
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  3. Edward S. Tobias
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  4. Robert McFarlane
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  5. Donald M. Black
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Correspondence to Donald M. Black.

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Hughes, K., Hurlstone, A., Tobias, E. et al. Absence of ST7 mutations in tumor-derived cell lines and tumors. Nat Genet 29, 380–381 (2001). https://doi.org/10.1038/ng783

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