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Sudden and unexpected

Infections have been implicated in sudden and unexpected deaths, but evidence of causality and insights into underlying mechanisms are lacking. Now, a new study in mice identifies a homeostatic mechanism that seems critical for stabilizing the host response after microbial infection.

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Figure 1: Comparison of physiological responses to endotoxemia in wild-type (right) and Kir6.1-deficient mice (left).


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Balling, R. Sudden and unexpected. Nat Genet 39, 1422–1423 (2007).

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