Human geneticists withhold judgment on any report of linkage or allelic association until it is independently replicated. But the independent replication criterion has become harder to meet. Does this signal the demise of the reverse genetics paradigm or a problem with the replication requirement itself?
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Vieland, V. The replication requirement. Nat Genet 29, 244–245 (2001). https://doi.org/10.1038/ng1101-244
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DOI: https://doi.org/10.1038/ng1101-244
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