Transcriptional cis-regulatory modules have a fundamental role in regulating eukaryotic gene expression. A new study shows how computational modeling can test hypotheses about how regulatory elements function, with results that challenge conventional views of their organization.
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Halfon, M. (Re)modeling the transcriptional enhancer. Nat Genet 38, 1102–1103 (2006). https://doi.org/10.1038/ng1006-1102
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DOI: https://doi.org/10.1038/ng1006-1102