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Choose your target

Nature Genetics volume 26, pages 159–161 (2000)Cite this article

Abstract

The technology of modifying endogenous genes has recently been extended from mice to Drosophila and sheep. Concurrently, genomic sequencing is uncovering thousands of previously uncharacterized genes. Armed with today's technologies, what are our best options for delineating the functions of these new genes?

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Figure 1: Gene targeting in Drosophila.
Figure 2: Gene targeting in sheep.

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Authors and Affiliations

  1. Department of Human Genetics, Howard Hughes Medical Institute, University of Utah School of Medicine, Salt Lake City , Utah, USA

    Mario R Capecchi

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  1. Mario R Capecchi
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Capecchi, M. Choose your target. Nat Genet 26, 159–161 (2000). https://doi.org/10.1038/82825

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