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Variation in KLK genes, prostate-specific antigen and risk of prostate cancer

Nature Genetics volume 40, pages 1032–1034 (2008)Cite this article

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Figure 1: Associations of tag SNPs in the KLK region with PSA concentrations and prostate cancer risk in the PLCO Trial.

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Acknowledgements

The Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (PLCO) is supported by the Intramural Research Program of the Division of Cancer Epidemiology and Genetics and by contracts from the Division of Cancer Prevention, National Cancer Institute (NCI), US National Institutes of Health (NIH), Department of Health and Human Services (DHHS). The Health Professionals Follow-up Study (HPFS) study is supported by NIH grants CA55075 and U01CA098233. The American Cancer Society (ACS) study is supported by U01 CA098710. The Alpha Tocopherol Beta-Carotene Cancer Prevention (ATBC) Study is supported by the Intramural Research Program of the National Cancer Institute, NIH, and by US Public Health Service contracts N01-CN-45165, N01-RC-45035 and N01-RC-37004 from the National Cancer Institute, NIH, DHHS. A.S.K is supported by RO1CA112028. The genome-wide scans have been supported by the NCI, NIH, under contract N01-CO-12400. The content of this publication does not necessarily reflect the views or policies of the DHHS, nor does mention of trade names, commercial products or organizations imply endorsement by the US government.

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Authors and Affiliations

  1. Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, 20892, Maryland, USA

    Jiyoung Ahn, Sonja I Berndt, Sholom Wacholder, Meredith Yeager, Demetrius Albanes, Gilles Thomas, David J Hunter, Joseph F Fraumeni Jr., Robert N Hoover, Stephen J Chanock & Richard B Hayes

  2. Department of Epidemiology, Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, 02115, Massachusetts, USA

    Peter Kraft & David J Hunter

  3. Division of Urologic Surgery, Washington University School of Medicine, St. Louis, 63110, Missouri, USA

    Adam S Kibel

  4. Department of Nutrition, Harvard School of Public Health, Boston, 02115, Massachusetts, USA

    Edward Giovannucci & Meir J Stampfer

  5. Department of Epidemiology, Harvard School of Public Health, Boston, 02115, Massachusetts, USA

    Edward Giovannucci & Meir J Stampfer

  6. Department of Medicine, Channing Laboratory, Brigham and Women's Hospital and Harvard Medical School, Boston, 02115, Massachusetts, USA

    Edward Giovannucci & Meir J Stampfer

  7. Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, FIN-0030, Finland

    Jarmo Virtamo

  8. Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, 30329, Georgia, USA

    Michael J Thun & Heather Spencer Feigelson

  9. CeRePP Hopital Tenon, Assistance Publique-Hôpitaux de Paris, Paris, 75020, France

    Geraldine Cancel-Tassin & Olivier Cussenot

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Correspondence to Richard B Hayes.

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Supplementary Figure 1, Supplementary Tables 1–6, Supplementary Methods (PDF 418 kb)

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Ahn, J., Berndt, S., Wacholder, S. et al. Variation in KLK genes, prostate-specific antigen and risk of prostate cancer. Nat Genet 40, 1032–1034 (2008). https://doi.org/10.1038/ng0908-1032

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