Microarray analysis greatly assists in defining functions of genes and elucidating important biological pathways. To enhance this power, a database or compendium of hundreds of gene-expression profiles was constructed using gene-deletion mutants of yeast. Statistical tools could then sift through the compendium to identify matching fingerprints of expression and thereby unearth, for example, therapeutic targets.
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Gullans, S. Of microarrays and meandering data points. Nat Genet 26, 4–5 (2000). https://doi.org/10.1038/79159
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DOI: https://doi.org/10.1038/79159
