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A step forward for restless legs syndrome

Two genome-wide association studies report three loci predisposing to restless legs syndrome, a common sleep disorder also associated with periodic limb movements during sleep. The identified variants account for a large portion of population-attributable risk in individuals of European ancestry and may preferentially affect various symptoms of the disorder.

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Mignot, E. A step forward for restless legs syndrome. Nat Genet 39, 938–939 (2007).

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