The molecular pathogenesis of most forms of amyotrophic lateral sclerosis (ALS) is poorly understood. Now, reduced expression of vascular endothelial growth factor (VEGF) is shown to be a risk factor for contracting ALS. Addition of Vegf in mice is shown to protect motoneurons from damage.
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Cleveland, J. A new piece of the ALS puzzle. Nat Genet 34, 357–358 (2003). https://doi.org/10.1038/ng0803-357
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DOI: https://doi.org/10.1038/ng0803-357
