Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Aurora and the hunt for cancer-modifying genes

Quantitative modifiers of neoplastic pathways are greatly treasured but difficult to identify at the molecular level. An apparent success has now identified a centrosomal protein kinase that affects many cancer histotypes.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Kinzler, K.W. & Vogelstein, B. Cell 87, 159–170 (1996).

    Article  CAS  Google Scholar 

  2. Gould, K.A. & Dove, W.F. Proc. Natl. Acad. Sci. USA 94, 5848–5853 (1997).

    Article  CAS  Google Scholar 

  3. Ewart-Toland, A. et al. Nat. Genet. 34, 403–412 (2003)

    Article  CAS  Google Scholar 

  4. Ruivenkamp, C.A. et al. Nat. Genet. 31, 295–300 (2002).

    Article  CAS  Google Scholar 

  5. Dietrich, W.F. et al. Cell 75, 631–639 (1993).

    Article  CAS  Google Scholar 

  6. Balmain, A. & Nagase, H. Trends Genet. 14, 139–144 (1998).

    Article  CAS  Google Scholar 

  7. Bischoff, J.R. & Plowman, G.D. Trends Cell Biol. 9, 454–459 (1999).

    Article  CAS  Google Scholar 

  8. Glover, D.M., Leibowitz, M.H., McLean, D.A. & Parry, H. Cell 81, 95–105 (1995).

    Article  CAS  Google Scholar 

  9. Sen, S., Zhou, H. & White, R.A. Oncogene 14, 2195–2200 (1997).

    Article  CAS  Google Scholar 

  10. Zhou, H. et al. Nat. Genet. 20, 189–193 (1998).

    Article  CAS  Google Scholar 

  11. Reich, D.E. et al. Nature 411, 199–204 (2001).

    Article  CAS  Google Scholar 

  12. Hudson, T.J. Nat. Genet. 33, 439–440 (2003).

    Article  CAS  Google Scholar 

  13. Dahlman, I. et al. Nat. Genet. 30, 149–150 (2002).

    Article  CAS  Google Scholar 

  14. Berry, R. et al. Am. J. Hum. Genet. 67, 82–91 (2000).

    Article  CAS  Google Scholar 

  15. Boveri, T. The Origin of Malignant Tumours (Williams and Wilkins, Baltimore, 1914).

    Google Scholar 

  16. Sibon, O.C. Nat. Genet. 34, 6–7 (2003).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Dove, W. Aurora and the hunt for cancer-modifying genes. Nat Genet 34, 353–354 (2003). https://doi.org/10.1038/ng0803-353

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/ng0803-353

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing