Until very recently, it was widely touted that the complete DNA sequences of any two human beings were 99.9% identical. A new study refutes this notion through a comprehensive comparison of two individual genomes which detects hundreds of new structural genomic variants.
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References
Iafrate, A.J. et al. Nat. Genet. 36, 949–951 (2004).
Sebat, J. et al. Science 305, 525–528 (2004).
Tuzun, E. et al. Nat. Genet. 37, 727–732 (2005).
Bailey, J.A. et al. Science 297, 1003–1007 (2002).
Cheung, J. et al. Genome Biol. 4, R25 (2003).
van Ommen, G.-J. B. Nat. Genet. 37, 333–334 (2005).
Morley, M. et al. Nature 430, 743–747 (2004).
Stefansson, H. et al. Nat. Genet. 37, 129–137 (2005).
Osborne, L.R. et al. Nat. Genet. 29, 321–325 (2001).
Gonzalez, E. et al. Science 307, 1434–1440 (2005).
Fredman, D. et al. Nat. Genet. 36, 861–866 (2004).
de la Chapelle, A. et al. Am. J. Hum. Genet. 26, 746–765 (1974).
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Lee, C. Vive la difference!. Nat Genet 37, 660–661 (2005). https://doi.org/10.1038/ng0705-660
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DOI: https://doi.org/10.1038/ng0705-660
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