Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

New susceptibility genes for ulcerative colitis

Genome-wide association studies in Crohn's disease have convincingly identified multiple risk variants. Two new studies in ulcerative colitis, a related inflammatory bowel disease, now reveal a glimpse of the overlapping spectrum of risk variants, highlighting both the commonalities and the unique features of these disorders.

This is a preview of subscription content, access via your institution

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

References

  1. Xavier, R.J. & Podolsky, D.K. Nature 448, 427–434 (2007).

    Article  CAS  Google Scholar 

  2. Satsangi, J. et al. Gut 38, 738–741 (1996).

    Article  CAS  Google Scholar 

  3. Fisher, S.A. et al. Nat. Genet. 40, 710–712 (2008).

    Article  CAS  Google Scholar 

  4. Franke, A. et al. Nat. Genet. 40, 713–715 (2008).

    Article  CAS  Google Scholar 

  5. Loftus, E.V., Jr. Gastroenterology 126, 1504–1517 (2004).

    Article  Google Scholar 

  6. Toruner, M. et al. Gastroenterology 134, 929–936 (2008).

    Article  Google Scholar 

  7. Wang, C.C. et al. Dev. Biol. 224, 152–167 (2000).

    Article  CAS  Google Scholar 

  8. Matsuda, A. et al. Oncogene 22, 3307–3318 (2003).

    Article  CAS  Google Scholar 

  9. Hamada, T. et al. Hum. Mol. Genet. 11, 833–840 (2002).

    Article  CAS  Google Scholar 

  10. Caccamo, D. et al. Arch. Pathol. Lab. Med. 118, 572–574 (1994).

    CAS  PubMed  Google Scholar 

  11. Lesage, S. et al. Am. J. Hum. Genet. 70, 845–857 (2002).

    Article  CAS  Google Scholar 

  12. van Heel, D.A. et al. Lancet 365, 1794–1796 (2005).

    Article  CAS  Google Scholar 

  13. Thomas, G.A., Rhodes, J. & Green, J.T. Am. J. Gastroenterol. 93, 144–149 (1998).

    CAS  PubMed  Google Scholar 

  14. Hunt, K.A. et al. Nat. Genet. 40, 395–402 (2008).

    Article  CAS  Google Scholar 

  15. Haiman, C.A. et al. Nat. Genet. 39, 954–956 (2007).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Dubois, P., van Heel, D. New susceptibility genes for ulcerative colitis. Nat Genet 40, 686–688 (2008). https://doi.org/10.1038/ng0608-686

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/ng0608-686

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing