The mitochondrial genomes of tumor cells accumulate mutations during transformation. A new study raises questions regarding the way in which mutations accumulate and has implications for the potential role of mitochondrial function in tumor phenotype.
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Augenlicht, L., Heerdt, B. Mitochondria: integrators in tumorigenesis?. Nat Genet 28, 104–105 (2001). https://doi.org/10.1038/88800
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DOI: https://doi.org/10.1038/88800
