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Chipping away at the genetics of smoking behavior

Nature Genetics volume 42, pages 366–368 (2010)Cite this article

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Three large consortia present comprehensive analyses that identify genetic factors influencing smoking initiation, intensity and cessation. The genetic architecture of these three phases of smoking behavior appears to be largely distinct.

Genetics by smoking stages

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Figure 1: Smoking behavior as a multistep process with genetic influences.

References

  1. Li, M.D. Curr. Psychiatry Rep. 8, 158–164 (2006).

    Article  CAS  Google Scholar 

  2. Thorgeirsson, T.E. et al. Nat. Genet. 42, 448–453 (2010).

    Article  CAS  Google Scholar 

  3. Liu, J.Z. et al. Nat. Genet. 42, 436–440 (2010).

    Article  CAS  Google Scholar 

  4. TAG Consortium. Nat. Genet. 42, 441–447 (2010).

  5. Fanous, S., Hammer, R.P. Jr. & Nikulina, E.M. Neuroscience published online, doi:10.1016/j.neuroscience.2010.02.064 (3 March 2010).

  6. Cazorla, M. et al. PLoS ONE. 5, e9777 (2010).

    Article  Google Scholar 

  7. Vink, J.M. et al. Am. J. Hum. Genet. 84, 367–379 (2009).

    Article  CAS  Google Scholar 

  8. Bierut, L.J. et al. Hum. Mol. Genet. 16, 24–35 (2007).

    Article  CAS  Google Scholar 

  9. Meyer, E.L., Yoshikami, D. & McIntosh, J.M. J. Neurochem. 105, 1761–1769 (2008).

    Article  CAS  Google Scholar 

  10. Klink, R., de Kerchove, d'Exaerde A., Zoli, M. & Changeux, J.P. J. Neurosci. 21, 1452–1463 (2001).

    Article  CAS  Google Scholar 

  11. Swan, G.E. et al. Pharmacogenet. Genomics 15, 115–125 (2005).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Margaret R. Spitz and Paul Cinciripini are at the Departments of Epidemiology and Behavioral Sciences, Christopher I. Amos, University of Texas MD Anderson Cancer Center, Houston, Texas, USA, and the Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, USA.,

    Christopher I Amos, Margaret R Spitz & Paul Cinciripini

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  1. Christopher I Amos
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  2. Margaret R Spitz
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  3. Paul Cinciripini
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Correspondence to Christopher I Amos.

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Competing interests

P. Cinciripini has received grant support from Pfizer, which manufactures vrenicline (Chantrix).

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Amos, C., Spitz, M. & Cinciripini, P. Chipping away at the genetics of smoking behavior. Nat Genet 42, 366–368 (2010). https://doi.org/10.1038/ng0510-366

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