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Maintaining imprinting

Nature Genetics volume 25, pages 4–5 (2000)Cite this article

The imprinting of a large cluster of paternally expressed genes at the Prader-Willi syndrome locus is established by an imprinting centre in human and mouse. Deletions carried by a member of a rare family and by chimaeric mice demonstrate that the imprinting centre is additionally required for postzygotic maintenance of paternal identity.

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Authors and Affiliations

  1. Howard Hughes Medical Institute and Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, 19104, Pennsylvania, USA

    Mellissa R W Mann & Marisa S Bartolomei

  2. Mellissa R W Mann & Marisa S Bartolomei

Authors
  1. Mellissa R W Mann
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  2. Marisa S Bartolomei
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Mann, M., Bartolomei, M. Maintaining imprinting. Nat Genet 25, 4–5 (2000). https://doi.org/10.1038/75575

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